Clarkton, Missouri has a humid subtropical climate with hot summers and mild winters. The annual precipitation is around 48 inches, with the majority falling in the spring and summer. Hydrology constituents in Clarkton include several creeks and streams, as well as the nearby St. Francis River. Outdoor recreation opportunities include fishing, hunting, and camping in the nearby Mark Twain National Forest. Additionally, the nearby Mingo National Wildlife Refuge offers opportunities for birdwatching and hiking. Clarkton is a small town with a population of just over 1,000 people, and it serves as a gateway to the natural beauty and outdoor activities of southeastern Missouri.