Clyde, Ohio has a humid continental climate with four distinct seasons. Summers are typically warm with temperatures averaging in the mid-80s°F, while winters are cold with temperatures averaging in the mid-20s°F. The area receives around 35 inches of rainfall annually, with the highest precipitation occurring during the summer months.

The hydrology of Clyde is characterized by the Sandusky River, which runs through the town and provides opportunities for fishing and boating. The river also serves as a source of drinking water for the town.

Outdoor recreation opportunities in Clyde include the Clyde Reservoir, which offers fishing and boating, as well as parks with hiking trails and sports facilities. The nearby Pickerel Creek Wildlife Area also provides opportunities for hunting and wildlife viewing.