Donaldsonville, Louisiana is located on the west bank of the Mississippi River and has a humid subtropical climate. Summers are hot and humid with highs in the 90s, while winters are mild with temperatures in the 60s. The area experiences high precipitation throughout the year, with an average annual rainfall of around 60 inches. Donaldsonville is also susceptible to hurricanes and flooding due to its proximity to the Gulf of Mexico and the Mississippi River.

The hydrology of Donaldsonville is dominated by the Mississippi River, which provides a source of water for the community. The river also offers outdoor recreation opportunities such as fishing, boating, and kayaking.

Other outdoor recreation opportunities in the area include visiting the Lake Verret Wildlife Refuge, which offers opportunities for hunting and fishing, as well as hiking and birdwatching. The nearby Bogue Chitto State Park also offers hiking, camping, and fishing opportunities in a scenic natural setting.