Greenwood, Mississippi is located in the Mississippi Delta region of the United States. The climate in Greenwood is humid subtropical, with hot summers and mild winters. The area is known for its fertile soil and abundance of water, with the Yazoo River and its tributaries providing important hydrology constituents for local agriculture.

Outdoor recreation opportunities in Greenwood include fishing, hunting, and boating on the nearby rivers and lakes. There are also several parks and nature trails for hiking and biking. The city is home to the Viking Cooking School, which offers classes and workshops for aspiring chefs. Greenwood is also known for its vibrant music scene, with several live music venues showcasing blues and jazz performers.