Hamilton is a small town located in northeastern Mississippi with a humid subtropical climate. Summers are hot and humid, while winters are mild with occasional snowfall. The town is situated near the Buttahatchee River, which is a tributary of the Tombigbee River. The water quality in the river is monitored for hydrology constituents, including nutrients, pathogens, and sediment.

Outdoor recreation opportunities in Hamilton include fishing, boating, and hiking. The nearby Dismals Canyon offers a unique experience for visitors to explore a sandstone gorge with waterfalls and bioluminescent creatures. The town is also home to the Marion County Lake, which is popular for fishing and camping. Overall, Hamilton provides a peaceful environment with access to natural beauty and outdoor activities.