Monticello, located in southern Mississippi, experiences a humid subtropical climate. Summers are hot and humid, with average temperatures ranging from the mid-70s to low 90s Fahrenheit. Winters are mild to cool, with temperatures ranging from the mid-30s to mid-60s Fahrenheit. The area receives abundant rainfall throughout the year, with the wettest months being March to May and the drier period occurring in the fall.

Monticello is situated near the Pearl River, which contributes to its hydrology. The river serves as a vital source of water and supports various aquatic species. Additionally, there are several lakes and ponds in the region, offering recreational activities like fishing, boating, and swimming.

Outdoor recreation opportunities in Monticello are abundant. The area is blessed with numerous forests and wildlife management areas, providing excellent settings for camping, hiking, and hunting. The Bienville National Forest, located nearby, offers trails for mountain biking and horseback riding. The Mississippi River, within a reasonable driving distance, provides opportunities for riverboat tours and water activities. Overall, Monticello provides a welcoming environment for nature enthusiasts and outdoor lovers.