Located in West Texas, Odell experiences a semi-arid climate characterized by hot summers and mild winters. Summers can be scorching with temperatures often exceeding 100°F, while winters are relatively mild, rarely dropping below freezing. The region receives low annual precipitation, averaging around 19 inches, mainly occurring during the summer months in the form of thunderstorms.

Odell lies within the Upper Brazos River Basin, with the Brazos River serving as the primary hydrological feature. The river provides water for irrigation, agriculture, and drinking purposes.

Outdoor recreation opportunities in Odell include fishing, boating, and swimming in the Brazos River. The area offers picturesque landscapes for hiking and camping enthusiasts, allowing visitors to explore the region's unique flora and fauna. Additionally, birdwatching is popular, as the area attracts various migratory bird species.