The Whitewater River Run from US 250 to McGee Run in West Virginia is a popular destination for whitewater enthusiasts. The ideal streamflow range for this run is between 700-1800 cfs, with the optimal range being 1000-1500 cfs. The class rating for this run ranges from Class II to Class IV, with the majority of rapids being Class II-III.

The segment mileage for this run is approximately 10 miles, taking around 4-6 hours to complete. Some of the specific river rapids and obstacles include "Triple Drop," "Davy Jones' Locker," "Rattlesnake," and "S-turns."

There are specific regulations to the area that must be followed, including wearing a personal flotation device at all times, not littering, and respecting private property along the riverbanks. Additionally, certain sections of the river may be closed during certain times of the year to protect fish spawning grounds.