Maximum discharge along the river is currently at the reporting a streamflow rate of cfs. This is also the highest stage along the Caloosahatchee River, with a gauge stage of ft at this location. This river is monitored from 0 different streamgauging stations along the Caloosahatchee River, the highest being situated at an altitude of ft, the .

The Caloosahatchee River is located in Southwest Florida and stretches for 67 miles from Lake Okeechobee to the Gulf of Mexico. It has a rich history, having been used by the Calusa Indians as a transportation route and later by Spanish explorers. Today, it serves as a source of water for agricultural irrigation and is used for recreational activities such as boating and fishing. The river's hydrology has been impacted by the construction of several dams, including the W.P. Franklin Lock and Dam, which regulates water levels and helps prevent flooding. The Caloosahatchee River also has several reservoirs, including the C-43 Reservoir and the Caloosahatchee Reservoir, which were built to store water and protect against drought. Despite efforts to mitigate pollution, the river remains vulnerable to algae blooms and other environmental threats.