Maximum discharge along the river is currently at the reporting a streamflow rate of cfs. This is also the highest stage along the Manatee River, with a gauge stage of ft at this location. This river is monitored from 1 different streamgauging stations along the Manatee River, the highest being situated at an altitude of ft, the .

The Manatee River is a 36-mile-long river located in Manatee County, Florida. It was named after the gentle sea cows that inhabit its waters. The river originates in eastern Manatee County, near the town of Duette, and flows westward into the Gulf of Mexico. The river's hydrology is heavily influenced by rainfall and tidal fluctuations. The river is dammed at two locations: the Lake Manatee Dam and the Myakka Head Dam. The Lake Manatee Dam was constructed in 1967 to create a reservoir that provides drinking water to the region. The Myakka Head Dam is an earthen dam that serves as a backup water supply. The river is used for recreational activities such as boating and fishing. The surrounding agricultural areas rely on the river for irrigation water. The river has a rich history, dating back to prehistoric times when it was inhabited by Indigenous people.