Maximum discharge along the river is currently at the reporting a streamflow rate of cfs. This is also the highest stage along the Tuckahoe River, with a gauge stage of ft at this location. This river is monitored from 1 different streamgauging stations along the Tuckahoe River, the highest being situated at an altitude of ft, the .

The Tuckahoe River is a 31-mile-long waterway that flows through Maryland's Caroline County. Historically, the river was used as a transportation route and a source of power for mills. Today, a portion of the river is protected as part of the Tuckahoe State Park. The river's hydrology is influenced by seasonal precipitation and land use, with much of the watershed being agricultural. There are two major reservoirs along the river's course, including the Tuckahoe Creek impoundment and the Andrewsville Dam. The Tuckahoe River supports a variety of recreational activities including fishing, kayaking, and canoeing. The river also provides irrigation to local farms and supports a diverse range of wildlife including bald eagles, ospreys, and muskrats.