The climate of Bethera is considered humid subtropical with mild winters and hot summers. The area is rich in water resources with creeks and wetlands abundant. The hydrology constituents consist of several watersheds that flow into the nearby Cooper River. Outdoor recreation opportunities in Bethera are plentiful, including fishing, boating, and kayaking along the creeks and waterways. The Francis Marion National Forest, located just a short drive from Bethera, offers hiking, camping, and wildlife viewing opportunities. The area is also known for its birdwatching, with several species of waterfowl, shorebirds, and raptors commonly spotted throughout the year.
Bethera receives approximately 1279mm of rain per year, with humidity levels near 86% and air temperatures averaging around 18°C. Bethera has a plant hardyness factor of , meaning plants and agriculture in this region thrive during a short period during spring and early summer. Most plants will die off during the colder winter months.