The climate in Cohoes is characterized by cold, snowy winters and mild summers with occasional thunderstorms. The hydrology of Cohoes is heavily influenced by the Mohawk River, which runs through the city and provides opportunities for fishing, boating, and other water-based activities. The river also plays a role in the city's history, as it was once a major transportation route for goods and people. Outdoor recreation opportunities in Cohoes include hiking and biking trails, parks and nature preserves, and a variety of sports and fitness activities offered by local clubs and organizations.
Cohoes receives approximately 1014mm of rain per year, with humidity levels near 79% and air temperatures averaging around 10°C. Cohoes has a plant hardyness factor of 5, meaning plants and agriculture in this region thrive during a short period during spring and early summer. Most plants will die off during the colder winter months.