Morehouse, Missouri is a small town located in New Madrid County in the southeastern part of the state. It experiences a humid subtropical climate with hot and humid summers and mild to cool winters. Summers in Morehouse are characterized by high temperatures averaging around 90°F (32°C) and occasional thunderstorms. Winters are generally mild, with temperatures averaging around 40°F (4°C), occasionally dropping below freezing.

The hydrology constituents of Morehouse are influenced by the nearby Mississippi River and its tributaries. This includes the St. John's Bayou, which flows through the town. These water bodies provide opportunities for fishing and boating activities. Anglers can expect to catch a variety of fish species, including bass, catfish, and crappie.

In terms of outdoor recreation, Morehouse boasts several parks and recreational areas. The city park offers amenities such as playgrounds, picnic areas, and sports fields, providing opportunities for family gatherings and outdoor activities. Additionally, the nearby Wappapello Lake offers more extensive opportunities for outdoor enthusiasts, including camping, hiking, swimming, and boating. The lake's scenic surroundings make it an ideal destination for nature lovers, providing a peaceful retreat from the bustling city life.