Neapolis, Ohio is a small village situated in Lucas County, in the northwestern part of the state. The village experiences a humid continental climate, characterized by warm summers and cold winters. Average temperatures range from the low 20s °F (-6 °C) in winter to the mid-80s °F (around 30 °C) in summer. Precipitation is evenly distributed throughout the year, with an annual average of around 32 inches (81 cm).

Hydrologically, Neapolis is located near the Maumee River, providing opportunities for outdoor recreation such as fishing, boating, and kayaking. The river is known for its diverse fish populations, including smallmouth bass, walleye, and catfish, attracting anglers from the area. Additionally, there are several parks and nature reserves nearby, offering beautiful trails for hiking and biking. Oak Opening Preserve Metropark, just a short drive away, features a unique ecosystem with rare plants and offers opportunities for birdwatching.

Overall, Neapolis, Ohio provides a pleasant climate for outdoor activities year-round, with its proximity to the Maumee River and nearby parks offering various recreational opportunities for nature enthusiasts.