The Whitewater River Run is a popular destination for whitewater enthusiasts in California. The ideal streamflow range for this section of the river is between 800 and 3,000 cfs. The segment covers 14.5 miles and is rated as Class III-IV, with some sections reaching Class V during high water. The run begins four-tenths of a mile upstream from the confluence of Foley Creek and ends at Trinity WSR.

The river rapids and obstacles to look out for include the "Cascades," "Chamberlain Falls," and "Hell's Half Mile." These rapids are all Class IV-V and require experienced paddlers to navigate safely.

There are specific regulations in place for the Whitewater River Run. Paddlers must wear a properly fitting US Coast Guard-approved personal flotation device (PFD) at all times while on the river, and helmets are strongly recommended. Additionally, camping is only allowed in designated areas, and fires are prohibited within 100 feet of the river.