The Whitewater River Run in Florida ranges from River Mile 23, where riverfront residential development begins, to the vicinity of Snook Haven Fish Camp at approximately River Mile 18. The ideal streamflow range for this section of the river is between 500-2000 cfs. This segment of the river is classified as Class II-III, meaning it has moderate to high rapids and requires moderate to advanced skill level for paddlers.

The river rapids and obstacles include numerous small drops and ledges, narrow and winding channels, and low overhanging tree branches. The river segment has several popular rapids, including "The Narrows," "The Twister," and "The Drop." Paddlers must use caution on this section of the river as the rapids can be challenging and require proper safety gear and technique.

Specific regulations to the area include the use of personal flotation devices (PFDs) at all times, a maximum of two people per vessel, and a strict no-alcohol policy. Additionally, motorized watercraft are prohibited on this section of the river. It is important to note that the river levels can change rapidly due to weather conditions, and paddlers should always check the current water levels and weather forecast before embarking on their journey.