The Whitewater River run in the Mt. Jefferson Wilderness Boundary to Confluence with Breitenbush River is a popular destination for experienced kayakers and rafters. The ideal streamflow range for this run is between 500 to 1,500 cfs, with the best time to go being in the spring after a snowmelt or after a heavy rain. The segment mileage for this run is approximately 10 miles, with a class rating of III-IV.

This run features several challenging rapids, including Big Brother, Little Brother, and the Nutcracker. The Big Brother rapid is a steep drop with a tight turn and requires precise maneuvering. Little Brother is a narrow, technical rapid with a strong eddy line. The Nutcracker is a complex series of drops and chutes that require careful planning and execution.

There are specific regulations that apply to this area, including permits for overnight camping and fire restrictions. It is important to check with the local ranger station for the most up-to-date information before planning a trip to this area.

Overall, the Whitewater River run is a challenging and rewarding destination for experienced kayakers and rafters. It is essential to have the proper equipment, skills, and knowledge of the area before attempting this run.