Maximum discharge along the river is currently at the reporting a streamflow rate of cfs. This is also the highest stage along the Wyaconda River, with a gauge stage of ft at this location. This river is monitored from 1 different streamgauging stations along the Wyaconda River, the highest being situated at an altitude of ft, the .

The Wyaconda River is a tributary of the Mississippi River, flowing for 133 miles through northeastern Missouri. Historically, the river played a significant role in the region's transportation and commerce, with steamboats navigating its waters in the 19th century. The river's hydrology is characterized by seasonal flooding, and specific reservoirs and dams have been constructed to manage flood control, such as the Wyaconda River Watershed Dam. The river is also important for irrigation and agriculture, supporting crops like soybeans, corn, and wheat. In terms of recreational use, the river offers opportunities for fishing and boating, with several public access points along its length.