The climate in Henderson is semi-arid, with hot summers and cold winters. The area receives an average annual precipitation of around 15 inches, mostly in the form of snow during the winter months. Henderson has few water resources, with most water coming from the South Platte River. Outdoor recreation opportunities in the area include hiking and biking in nearby state parks, fishing in the South Platte River, and golfing at the Riverdale Golf Course. Additionally, the town is located within a short drive of the Rocky Mountains, providing easy access to skiing and other winter activities.
Henderson receives approximately 362mm of rain per year, with humidity levels near 50% and air temperatures averaging around 11°C. Henderson has a plant hardyness factor of 5, meaning plants and agriculture in this region thrive during a short period during spring and early summer. Most plants will die off during the colder winter months.