Preston, Mississippi is a small town located in Kemper County, in the eastern part of the state. The climate in Preston is classified as humid subtropical, with hot and humid summers and mild winters. Average high temperatures range from the upper 80s in summer to the mid-50s in winter, while average lows range from the upper 60s in summer to the mid-30s in winter. The area receives moderate rainfall throughout the year.

Hydrology constituents in Preston are primarily influenced by the nearby Tombigbee River, which runs along the western edge of the town. The river provides opportunities for fishing, boating, and other water-based activities. Additionally, there are several creeks and smaller bodies of water in and around Preston, contributing to the overall hydrological landscape.

Outdoor recreation opportunities are abundant in Preston and its surrounding areas. The Tombigbee National Forest, situated nearby, offers opportunities for hiking, camping, and wildlife observation. Other activities such as hunting, birdwatching, and ATV riding are also popular in the region. The town's scenic surroundings and close proximity to natural areas make it an attractive destination for outdoor enthusiasts.