Sessums, Mississippi is a small rural community located in Oktibbeha County. The town is characterized by its warm and humid climate, typical of the southern United States. Summers in Sessums are hot, with average temperatures ranging from the mid-80s to low 90s Fahrenheit, while winters are mild, with temperatures averaging in the 40s and 50s.

Sessums is situated near the Noxubee River, which serves as one of the primary hydrological features of the area. The river contributes to the region's hydrology constituents, providing a water source for agriculture, wildlife habitats, and recreational activities. Fishing is a popular pastime in Sessums, with the Noxubee River offering opportunities to catch a variety of fish species, including bass, catfish, and crappie.

Outdoor recreation opportunities in Sessums include exploring the nearby Noxubee National Wildlife Refuge, which spans over 48,000 acres and offers hiking, birdwatching, and wildlife viewing opportunities. The refuge is home to numerous species, including deer, alligators, and migratory birds. Additionally, the area around Sessums provides ample opportunities for hunting, camping, and boating, allowing residents and visitors to enjoy the natural beauty of the region.