Sherman, Mississippi, located in the northeastern part of the state, experiences a humid subtropical climate. Summers are hot and humid, with average temperatures ranging from the upper 80s to low 90s Fahrenheit. Winters are generally mild, with average temperatures in the 40s and 50s. The area receives a moderate amount of rainfall throughout the year, with the wettest months being March, April, and May.

Hydrology constituents in Sherman are primarily influenced by the nearby Tombigbee River, which flows to the east of the town. The river provides a source of water for irrigation and recreational activities like fishing and boating. Additionally, there are several lakes and reservoirs in the surrounding area, including Lake Lamar Bruce and Lake Monroe, which offer opportunities for water-based recreational activities.

Outdoor recreation enthusiasts in Sherman can take advantage of the town's proximity to the Tanglefoot Trail, a popular 43-mile rail-trail that provides opportunities for hiking, biking, and horseback riding. The trail passes through picturesque landscapes, including forests, farmlands, and quaint small towns. For those interested in wildlife viewing, the nearby Holly Springs National Forest offers various opportunities to explore its diverse ecosystem and enjoy activities like birdwatching and camping.