The Whitewater River Run in Florida is a popular destination for kayakers and rafters looking for a challenging ride. The ideal streamflow range for this section of the river is between 200 and 500 cubic feet per second (cfs), with higher flows providing more difficult rapids. The segment covers approximately 10 miles of river, starting at approximately River Mile 18 and ending just upstream of the US 41 Highway Crossing.

The Whitewater River Run is rated as a Class III-IV rapids section, featuring several technical rapids and obstacles that require experience and skill to navigate safely. Some of the notable rapids on this segment include "The Maze," "Broken Paddle," and "Jaws." These rapids are known for their tight turns, steep drops, and powerful hydraulics.

Regulations for the area include a permit requirement for commercial outfitters and a ban on alcohol consumption while on the river. Additionally, visitors are advised to wear proper safety gear and to be aware of potential hazards such as submerged logs and rocks.

Overall, the Whitewater River Run is an exciting and challenging section of river that requires experience and skill to navigate safely. Visitors should be prepared for technical rapids and changing water conditions, and should always prioritize safety while on the water.