The Whitewater River Run from Leavitt Meadows Campground to HTNF Boundary in Nevada is a popular spot for kayaking, rafting, and fishing. The ideal streamflow range for this run is between 200-400 cubic feet per second (cfs), which is typically during the months of May and June. The class rating for this run is Class II-III, with mild to moderate rapids and obstacles. The segment mileage for this run is approximately 10 miles, and takes around 3-4 hours to complete.

One of the main rapids on this run is known as "Upper and Lower Toadstool," which is a Class III rapid that requires precise maneuvering through boulders and rocks. Another notable obstacle is "Big Rock Drop," which is a Class II rapid that requires avoiding a large rock in the middle of the river.

In terms of regulations, all participants are required to wear a properly fitting personal flotation device (PFD) at all times while on the river. Additionally, all boats must have a U.S. Coast Guard-approved throwable device on board, and no glass containers are allowed on the river.