The Rogue River in Oregon is a popular whitewater destination, with the section from the wilderness boundary to the confluence with the North Fork Rogue River being particularly exciting. The ideal streamflow range for this section is between 1,500 and 3,000 cubic feet per second (cfs), although experienced kayakers may enjoy higher flows. The class rating for this section is mostly class III and IV rapids, with some class V rapids in high water. The segment mileage is approximately 34 miles.

Some of the notable rapids and obstacles on this section include Rainie Falls, a class V rapid with a tricky line and a large hydraulic at the bottom, Blossom Bar, a class IV rapid with a narrow chute and a large hole at the bottom, and Upper and Lower Black Bar Falls, two class IV drops that can be portaged if necessary.

There are several regulations to be aware of when planning a trip on the Rogue River. Permits are required for all overnight trips, and campsites must be reserved in advance. Fires are not allowed except in designated fire rings, and all waste must be packed out. Additionally, there are fishing restrictions in certain areas to protect native fish populations.