Some of the most popular fish species found in the lake include largemouth bass, crappie, bluegill, catfish, and redear sunfish. Fishing tips for Cherokee Lake include using live bait, casting near drop-offs and underwater structures, and fishing during early morning or late evening hours. The best time to visit Cherokee Lake is during the spring and fall months when temperatures range from 60-80°F. Nearby activities include hiking, camping, and boating. Overall, Cherokee Lake is a great destination for fishing enthusiasts looking for a peaceful retreat.