The Middle Fork of the San Juan River, located in southwestern Colorado, offers a challenging whitewater experience for experienced paddlers. The ideal streamflow range for this run is between 700 and 1500 cfs. The river has a class III to IV rating, with segments ranging in mileage from 13 to 32 miles. The river is known for its technical rapids, including "Rocky Wall," "Devil's Punchbowl," and "Pine Tree." Paddlers should also be aware of obstacles such as logjams and strainers.

The Middle Fork is part of the Weminuche Wilderness Area, which has specific regulations that paddlers must follow. These regulations include practicing Leave No Trace principles, camping only in designated areas, and obtaining a permit through the San Juan National Forest. Additionally, boaters should be aware of a seasonal closure from March 1 to May 31 to protect wintering big game.

Overall, the Middle Fork of the San Juan River is a challenging and rewarding whitewater run for experienced paddlers. It is important to carefully consider the specific regulations and obstacles before embarking on this adventure.