The Lower Branch of the Whitewater River run is located in Section 28, T33N, R3E, while the Upper Branch runs from Section 15, T33N, R3E, to Section 7, T32N, R4E, in Colorado. The ideal streamflow range for this river run is between 300 and 1000 cubic feet per second (cfs). The Lower Branch is rated as a class III-IV run, while the Upper Branch is a class IV-V run. The segment mileage for the Lower Branch is 6.5 miles, while the Upper Branch spans 7 miles.

The Lower Branch features several challenging rapids like the Jaws, a tight chute with a steep drop, and the Meatgrinder, a large hole that can trap paddlers. The Upper Branch has several Class V rapids, such as the S-turn, a steep drop down a narrow chute, and the Sledgehammer, a large, powerful rapid with a sharp turn.

There are no specific regulations to the area, but it is recommended to obtain a permit from the Bureau of Land Management before accessing the river. It is also advised to wear proper safety equipment, such as a helmet and personal flotation device, and to paddle with a group.