The Whitewater River Run begins where the Lost River becomes the Cacapon River and flows for approximately 10 miles to Wardensville, West Virginia. The ideal streamflow range for this section of the river is between 150-300 cubic feet per second (cfs). The river is rated as a Class II-III, with several rapids and obstacles along the way. The first rapid is called "The Falls," which is a Class III rapid with a drop of approximately 5 feet. Other notable rapids include "S-Turn," "Pinball," and "Scissors." The river also features several large boulders and eddies that require skilled maneuvering.

Specific regulations apply to this area, including a catch-and-release policy for all fish caught in the river. Additionally, all boats must have proper safety equipment, including personal flotation devices (PFDs) for all passengers. The National Park Service also recommends paddlers to avoid this section of the river during high water levels, as it can become dangerous and difficult to navigate.

In summary, the Whitewater River Run is a challenging and exciting 10-mile section of river that requires skilled paddling and proper safety equipment. With Class II-III rapids and several large boulders and eddies, it is a popular destination for experienced paddlers looking for a fun and challenging adventure. It is important to follow all regulations and guidelines set forth by the National Park Service to ensure a safe and enjoyable experience.