The Whitewater River run in California is a popular destination for whitewater enthusiasts. The ideal streamflow range for this segment is between 400-1200 cfs. The segment is rated as a Class III-IV, which means it has moderate to difficult rapids with narrow passages that require precise maneuvering. The run covers a distance of one-eighth mile downstream from the confluence with Cherokee Creek to one-quarter mile upstream from the confluence with Slate Creek.

There are several notable rapids and obstacles on this stretch of the river, including the Meatgrinder, which is a Class IV rapid that features a series of drops and chutes. Other notable rapids include Son of Meatgrinder, Devil's Toenail, and Zootsuit. The run also features several pools and calm sections, which provide opportunities for rest and relaxation.

There are specific regulations that apply to the Whitewater River run. For example, all boaters must wear a personal flotation device (PFD) at all times while on the river. Additionally, motorized boats are not allowed on this section of the river. Boaters should also be aware of private property boundaries and avoid trespassing.