The Sixes River is a popular whitewater river run located in the state of Oregon. The ideal streamflow range for this river is between 800 and 3,000 cfs, which typically occurs during the spring months. The river is rated as a Class III-IV, making it suitable for intermediate to advanced paddlers. The segment mileage for this river is approximately 15 miles and includes several notable rapids and obstacles such as the infamous Devil's Staircase and the Big Mama Rapid.

In addition to the challenging rapids, the Sixes River is known for its stunning scenery, with lush forests and rugged cliffs lining the riverbanks. Visitors should be aware of specific regulations for the area, such as a permit requirement for overnight camping and limitations on group sizes. It is also important to respect local wildlife, as the Sixes River is home to a variety of species, including bald eagles and black bears.

Overall, the Sixes River is a thrilling whitewater run with breathtaking scenery, making it a must-visit for experienced paddlers seeking an adventure in the Pacific Northwest.