The Whitewater River Run from Headwaters Of North Yuba River to One-Eighth Mile Downstream Of Confluence With Cherokee Creek in California is a popular destination for kayakers and rafters. The ideal streamflow range for this run is between 500 and 1500 cfs, with the best time for this being in the spring months of April to June. The class rating for this run is class III to IV, making it suitable for intermediate to advanced paddlers. The segment mileage for this run is approximately 9.5 miles, with several challenging rapids and obstacles along the way.

One of the most challenging rapids is called the "Staircase" which is a series of drops and ledges that require precise navigation. Other notable rapids include "Butcher's Slot" and "Ramshorn". It is important to note that this run requires a permit from the Tahoe National Forest, and the use of motorized boats is prohibited. Additionally, there are strict regulations regarding litter and camping, as well as restrictions on the use of alcohol and drugs. Paddlers are advised to familiarize themselves with these regulations before undertaking this run.