North Carolina offers a diverse range of freshwater and saltwater fishing opportunities, making it a popular destination for anglers. Some of the state's most popular angling destinations include Lake Norman, Lake Gaston, the Roanoke River, and the Outer Banks. A variety of fish species can be found in the state, including largemouth and smallmouth bass, crappie, catfish, trout, and red drum.

The best time of year to fish in North Carolina varies depending on the species of fish and location. Generally, spring and fall are the best seasons for fishing, with average temperatures ranging from the low 60s to the low 80s. In the summer, temperatures can reach the high 80s and low 90s, making early morning and late evening fishing the most comfortable.

Recommended baits and lures depend on the species of fish being targeted. For bass, plastic worms and crankbaits are popular choices, while live bait such as minnows or worms are recommended for catfish. For saltwater fishing, shrimp, crabs, and squid are commonly used.

Interesting fishing facts about North Carolina include the state's recognition as the "Sailfish Capital of the World," with the Outer Banks being a prime location for sailfish fishing. Additionally, the state record for the largest catfish caught is held by a fisherman who caught a 117-pound blue catfish in Lake Gaston.